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Results for "

E3 ligase Ligand 4

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-41547
    Thalidomide 4-fluoride

    Cereblon Ligand 4; E3 ligase Ligand 4

    		 Ligands for E3 Ligase Cancer
    Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966) .
    Thalidomide 4-fluoride
  • HY-139656
    cIAP1 ligand 4

    		Ligands for E3 Ligase Cancer
    cIAP1 ligand 4 is a ligand for E3 ligase that can be used in the synthesis of PROTACs.
    cIAP1 ligand 4
  • HY-129619
    SNIPER(ER)-87

    		SNIPERs Estrogen Receptor/ERR Cancer
    SNIPER(ER)-87 consists of an inhibitor of apoptosis protein (IAP) ligand LCL161 derivative that is conjugated to the estrogen receptor α (ERα) ligand 4-hydroxytamoxifen by a PEG linker, and efficiently degrades the ERα protein (IC50=0.097 μM). SNIPER(ER)-87 preferentially recruits XIAP to ERα in the cells, and XIAP is the primary E3 ubiquitin ligase responsible for the SNIPER(ER)-87-induced ERα degradation .
    SNIPER(ER)-87

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